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Most studies were conducted on the effect of probiotics in both genders. This review presents intricate relationships among microbiota, the stomach, and the brain, along with recent research findings on the impact of probiotics and prebiotics on mental disorders. This review aims to comprehensively evaluate the current evidence on the role of prebiotics, probiotics, synbiotics, and postbiotics—collectively referred to as “biotics”—in modulating the human gut microbiota and enhancing intestinal epithelial integrity.
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The aim of this report is therefore to review the role of the gut microbiota in metabolic health and disease and the effects of prebiotics and probiotics on the gut microbiome and their therapeutic role, integrating a broad understanding of physiological mechanisms with a clinical perspective. To date, to our knowledge, however, there has not been any synthesis of the overall strength and caliber of this evidence. Oral supplementation with probiotics, prebiotics, and synbiotics is a novel potential complementary therapy for addressing overweight and obesity through gut microbiota modulation
This systematic review provides a comprehensive summary of the existing evidence to guide future research.
While probiotics and synbiotics have shown potential benefits in metabolic health, their specific effects on blood pressure (bp) regulation in this population remain unclear This study aims to evaluate the impact of probiotics and synbiotics supplementation on bp control in adults with prediabetes and t2dm, addressing this critical knowledge gap.
